Silver nanospheres bụ cytotoxic na genotoxic nye mkpụrụ ndụ azụ

Ndị edemede: Mark J. Spalding, John Pierce Wise Sr., Britton C. Goodale, Sandra S. Wise, Gary A. Craig, Adam F. Pongan, Ronald B. Walter, W. Douglas Thompson, Ah-Kau Ng, AbouEl- Makarim Aboueissa, Hiroshi Mitani, na Michael D. Mason
Aha mbipụta: Aquatic Toxicology
Ụbọchị mbipụta: Tọzdee, Eprel 1, 2010

A na-enyocha nanoparticles maka ọtụtụ ngwa n'ihi njirimara anụ ahụ ha pụrụ iche. Dịka ọmụmaatụ, a na-eji nanoparticles ọlaọcha mee ihe na ngwaahịa azụmahịa maka ihe ndị na-egbu egbu na antifungal. Ụfọdụ n'ime ngwaahịa ndị a nwere ike ịkpata nanoparticles ọlaọcha rute gburugburu mmiri. Dị ka nke a, nanoparticles na-ebute nchegbu ahụike maka ụmụ mmadụ na ụdị mmiri. Anyị jiri eriri cell medaka (Oryzias latipes) nyochaa cytotoxicity na genotoxicity nke 30 nm dayameta silver nanospheres. Ọgwụgwọ nke 0.05, 0.3, 0.5, 3 na 5 μg/cm2 kpalitere 80, 45.7, 24.3, 1 na 0.1% nlanarị, n'otu n'otu, n'otu ógbè na-emepụta nyocha. Ngwakọta ọla ọcha kpatakwara chromosomal aberrations na aneuploidy. Ọgwụgwọ nke 0, 0.05, 0.1 na 0.3 μg/cm2 kpatara mmebi na 8, 10.8, 16 na 15.8% nke metaphases na 10.8, 15.6, 24 na 24 ngụkọta aberrations na 100 metaphases, otu n'otu. Ihe data ndị a na-egosi na nanoparticles ọlaọcha bụ cytotoxic na genotoxic na mkpụrụ ndụ azụ.

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