Silver nanospheres is cytotoxic uye genotoxic kumasero ehove

Vanyori: Mark J. Spalding, John Pierce Wise Sr., Britton C. Goodale, Sandra S. Wise, Gary A. Craig, Adam F. Pongan, Ronald B. Walter, W. Douglas Thompson, Ah-Kau Ng, AbouEl- Makarim Aboueissa, Hiroshi Mtani, and Michael D. Mason
Zita Rakabudiswa: Aquatic Toxicology
Zuva Rokuburitswa: China, Kubvumbi 1, 2010

Nanoparticles iri kuongororwa zvakanyanya kune dzakasiyana siyana dzekushandisa nekuda kweiyo yakasarudzika yemuviri zvimiro. Semuenzaniso, sirivheri nanoparticles inoshandiswa muzvigadzirwa zvekutengesa kune yavo antibacterial uye antifungal properties. Zvimwe zvezvigadzirwa izvi zvinogona kukonzera sirivheri nanoparticles inosvika kunharaunda yemvura. Saka nekudaro, nanoparticles inokonzeresa hutano hwevanhu uye zvisikwa zvemumvura. Takashandisa medaka (Oryzias latipes) cell line kuongorora cytotoxicity uye genotoxicity ye30 nm dhayamita sirivheri nanospheres. Kurapa kwe0.05, 0.3, 0.5, 3 uye 5 μg/cm2 kwakakonzera 80, 45.7, 24.3, 1 uye 0.1% kupona, zvichiteerana, mune imwe koloni inogadzira assay. Silver nanoparticles zvakare yakakonzera chromosomal aberrations uye aneuploidy. Kurapa kwe0, 0.05, 0.1 uye 0.3 μg/cm2 kwakakonzera kukuvara mu8, 10.8, 16 uye 15.8% yemametaphases uye 10.8, 15.6, 24 uye 24 yakazara aberrations mu100 metaphases, zvichiteerana. Iyi data inoratidza kuti sirivheri nanoparticles ndeye cytotoxic uye genotoxic kumasero ehove.

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