Nanospheres Silver waa cytotoxic iyo genotoxic ilaa unugyada kalluunka

Qorayaasha: Mark J. Spalding, John Pierce Wise Sr., Britton C. Goodale, Sandra S. Wise, Gary A. Craig, Adam F. Pongan, Ronald B. Walter, W. Douglas Thompson, Ah-Kau Ng, AbouEl- Makarim Aboueissa, Hiroshi Mitani, iyo Michael D. Mason
Magaca Daabacaadda: Cilmiga Sunta Biyaha
Taariikhda daabacaada: Khamiis, Abriil 1, 2010

Nanoparticles ayaa si weyn loogu baarayaa codsiyo kala duwan iyadoo ay ugu wacan tahay sifooyinkooda gaarka ah. Tusaale ahaan, nanoparticles qalin ah ayaa loo isticmaalaa alaabada ganacsiga ee bakteeriyada iyo antifungal. Qaar ka mid ah alaabtan waxay u badan tahay inay keenaan nanoparticles qalin ah oo gaadha deegaanka biyaha. Sidan oo kale, nanoparticles ayaa walaac caafimaad u keena dadka iyo noocyada biyaha. Waxaan isticmaalnay khadka unugyada medaka (Oryzias latipes) si aan u baarno cytotoxicity iyo genotoxicity ee 30 nm dhexroor nanospheres silver. Daawaynta 0.05, 0.3, 0.5, 3 iyo 5 μg/cm2 waxay keentay 80, 45.7, 24.3, 1 iyo 0.1% badbaadada, siday u kala horreeyaan, gumaysi samaynaysa baaritaan. Nanoparticles Silver sidoo kale waxay keeneen aberrations koromosoomyada iyo aneuploidy. Daawaynta 0, 0.05, 0.1 iyo 0.3 μg/cm2 waxay dhaawacday 8, 10.8, 16 iyo 15.8% metaphases iyo 10.8, 15.6, 24 iyo 24 wadarta aberrations ee 100 metaphases, siday u kala horreeyaan. Xogtaasi waxay muujinaysaa in nanoparticles qalinku ay yihiin cytotoxic iyo genotoxic ilaa unugyada kalluunka.

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