Ama-nanospheres esiliva ayi-cytotoxic kanye ne-genotoxic kumaseli ezinhlanzi

Ababhali: Mark J. Spalding, John Pierce Wise Sr., Britton C. Goodale, Sandra S. Wise, Gary A. Craig, Adam F. Pongan, Ronald B. Walter, W. Douglas Thompson, Ah-Kau Ng, AbouEl- Makarim Aboueissa, Hiroshi Mtani, and Michael D. Mason
Igama Lokushicilela: I-Aquatic Toxicology
Usuku Lokushicilela: ULwesine, Ephreli 1, 2010

Ama-Nanoparticles aphenywa kabanzi ngezinhlelo eziningi ezahlukahlukene ngenxa yezakhiwo zawo eziyingqayizivele. Isibonelo, ama-nanoparticles esiliva asetshenziswa emikhiqizweni yezentengiselwano ngezindawo zabo zokulwa namagciwane kanye ne-antifungal. Eminye yale mikhiqizo kungenzeka ibangele ama-nanoparticles esiliva afinyelele endaweni ehlala emanzini. Ngakho-ke, ama-nanoparticles abangela ukukhathazeka kwezempilo kubantu nezilwane zasemanzini. Sisebenzise ulayini weseli we-medaka (Oryzias latipes) ukuze siphenye i-cytotoxicity kanye ne-genotoxicity yama-nanospheres esiliva angu-30 nm ububanzi. Ukwelashwa kwe-0.05, 0.3, 0.5, 3 kanye no-5 μg/cm2 kwenze u-80, 45.7, 24.3, 1 kanye no-0.1% ukusinda, ngokulandelana, kukholoni eyenza ukuhlolwa. Ama-nanoparticles esiliva aphinde adala ukuphazamiseka kwe-chromosomal kanye ne-aneuploidy. Ukwelashwa kwe-0, 0.05, 0.1 kanye ne-0.3 μg/cm2 kwenze umonakalo ku-8, 10.8, 16 kanye no-15.8% wama-metaphases kanye no-10.8, 15.6, 24 kanye no-24 okuphelele kokuhlukana kuma-metaphase angu-100, ngokulandelana. Le datha ibonisa ukuthi ama-nanoparticles esiliva ayi-cytotoxic kanye ne-genotoxic kumaseli ezinhlanzi.

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