Silver nanospheres ndi cytotoxic ndi genotoxic ku maselo a nsomba

Olemba: Mark J. Spalding, John Pierce Wise Sr., Britton C. Goodale, Sandra S. Wise, Gary A. Craig, Adam F. Pongan, Ronald B. Walter, W. Douglas Thompson, Ah-Kau Ng, AbouEl- Makarim Aboueissa, Hiroshi Mitani, and Michael D. Mason
Dzina Lofalitsidwa: Aquatic Toxicology
Tsiku Lofalitsidwa: Lachinayi, April 1, 2010

Nanoparticles akufufuzidwa kwambiri chifukwa cha ntchito zosiyanasiyana chifukwa cha mawonekedwe awo apadera. Mwachitsanzo, ma nanoparticles asiliva amagwiritsidwa ntchito pazinthu zamalonda chifukwa cha antibacterial ndi antifungal properties. Zina mwazinthuzi zitha kupangitsa kuti ma nanoparticles asiliva afikire chilengedwe chamadzi. Chifukwa chake, ma nanoparticles amakhudza thanzi la anthu ndi zamoyo zam'madzi. Tidagwiritsa ntchito medaka (Oryzias latipes) cell line kuti tifufuze za cytotoxicity ndi genotoxicity ya 30 nm diameter silver nanospheres. Kuchiza kwa 0.05, 0.3, 0.5, 3 ndi 5 μg / cm2 kunapangitsa 80, 45.7, 24.3, 1 ndi 0.1% kupulumuka, motero, mu colony kupanga assay. Silver nanoparticles adapangitsanso kuti chromosomal aberration ndi aneuploidy. Kuchiza kwa 0, 0.05, 0.1 ndi 0.3 μg / cm2 kunayambitsa kuwonongeka mu 8, 10.8, 16 ndi 15.8% ya metaphases ndi 10.8, 15.6, 24 ndi 24 kutayika kwathunthu mu 100 metaphases, motero. Izi zikuwonetsa kuti nanoparticles zasiliva ndi cytotoxic ndi genotoxic ku maselo a nsomba.

Werengani lipoti apa